What is AEFI?
Adverse event following immunization (AEFI) is defined as any untoward medical occurrence which follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine.
The adverse event may be any unfavorable or unintended sign, abnormal laboratory finding, symptom or disease.
What is vaccine vial monitor?
VVM is a small label stuck on the vial of a vaccine which changes color as the vaccine vial is exposed to heat.
The color of the VVM central square indicates if the vaccine is safe for use or not. It is a small light purple circle with a white square in the center. The square remains white if there is no exposure to heat. With heat exposure the square begins to darken. It registers the cumulative heat exposure over time.
Concentration of vitamin A in the solution
1,00,000 IU per mL
Which is the oil used
Arachis oil (peanut oil)
A total of how many doses are recommended.
Nine doses till 5 years of age.
The spoon supplied with the bottle has amarking inside. This indicates a volume of 1 mL.Completely filled spoon measures 2 mL.
Whether part of NIS?
Yes
Type of vaccine
Rabies vaccine (Fig. 4.14) is a killed vaccine. verorab insert
Two types of rabies vaccines are available; cell culture vaccines (CCVs) or Embryonated egg-based vaccine (EEV).
1. Cell Culture Vaccines
a) Human Diploid Cell Vaccine (HDCV), Liquid (Adsorbed), I.M dose; 1ml
b) Purified Chick Embryo Cell Vaccine (PCECV), I.M dose; 1ml
c) Purified Vero Cell Rabies Vaccine (PVRV), I.M. 0.5ml or 1ml (depends on the manufacturer)
Pneumococcal Conjugate vaccine has been introduced in the NIS under UIP since May 2017.
In the first phase, the vaccine was rolled out in Himachal Pradesh and parts of Bihar and Uttar Pradesh. Introduction in Madhya Pradesh and Rajasthan will follow and eventually be expanded to the country.
Vaccine Type: killed, conjugate vaccine
13 serotypes are individually conjugated to a nontoxic variant of diphtheria toxin.
It is a liquid preparation. After shaking, the vaccine is a homogenous, white suspension.
Currently, there are three types of JE vaccines in use:
1. The mouse brain-derived inactivated (Killed) vaccine.
2. The cell culture-derived inactivated (Killed) vaccine.
3. The cell culture-derived live, attenuated vaccine using SA 14-14-2 strain of JE virus.
Under the National program, the live attenuated (SA 14-14-2), cell culture-derived vaccine is used in India. It is presently manufactured in P. R. China. It is imported from there for use in India.
Type of vaccine
Killed, recombinant type
Route of administration
Intramuscular injection
Dose
0.5 mL till 10 years of age; adult dose: 1 mL
Diluent
None
Side effects
Soreness, erythema, induration, fatigue, fever, malaise, influenza-like symptoms.
Less common systemic reactions include nausea, vomiting, diarrhea, abdominal pain, abnormal liver function tests, arthralgia, myalgia, rash, pruritus and urticaria.website, insert
Measles containing vaccines are available either as monovalent measles vaccine or in combination with rubella (MR) or mumps and rubella (MMR) vaccines and with mumps, rubella and varicella (MMRV) vaccine.
Measles, MR and MMR have been used under NIS. Presently, MR vaccine is to be made available under routine immunization across the country.
99DOTS has been launched in India to track adherence of TB/HIV co-infected patients
It is an initiative under TB-HIV coordination
Oral poliovirus vaccines (OPV) have been the mainstay in the fight against polio. There are different types of oral poliovirus vaccine, which may contain one (mOPV), a combination of two (bOPV), or all the three (tOPV) serotypes of attenuated poliovirus.
